Amgen Inc.: Comparable Company Analysis for Enhanced Valuation Insights
- Lorenzo Agostini
- Nov 8, 2024
- 8 min read
Updated: Mar 23
Executive Summary
Building upon our prior Discounted Cash Flow (DCF) analysis, this report incorporates a Comparable Company Analysis (CCA) to provide a more comprehensive assessment of Amgen Inc.'s valuation within the Drug Manufacturers - General Healthcare subsector. The CCA facilitates a comparative evaluation of Amgen's market standing relative to other large-cap peers, leveraging key valuation metrics such as EV/EBITDA, EV/Earnings, and P/E ratios. These metrics serve as industry benchmarks for appraising Amgen’s relative valuation.
Additionally, this report integrates a sensitivity analysis from our previous study, which explores the influence of varying Weighted Average Cost of Capital (WACC) and growth assumptions on Amgen's intrinsic value.
The combination of intrinsic and market-based valuation methodologies offers investors a robust, dual-lens perspective for assessing Amgen’s current market price.
1. Rationale for Comparable Company Analysis (CCA)
The CCA approach provides a market-based perspective that complements the intrinsic valuation from DCF. While the DCF analysis estimates intrinsic value based on Amgen's projected cash flows, the CCA assesses Amgen’s relative value by comparing it to peers, offering insights into how the market currently values companies with similar operational profiles and financial performance.
In the healthcare sector, and particularly in the Drug Manufacturers - General subsector, a combination of stable revenue growth, defensive positioning, and regulatory influence often shapes valuations. Investors frequently look to peers to understand sector trends, and the selected peer group here—Eli Lilly, Johnson & Johnson, AbbVie, Merck, Novartis, Pfizer, Sanofi, Gilead, GSK, and Biogen—represents large-cap firms with market presence and substantial therapeutic portfolios. Although AstraZeneca is also a large-cap company, it was excluded from this analysis due to differences in its profile relative to the defined peer group.
2. Comparable Companies Overview
The tables below provide an overview of general company information and key financial metrics for Amgen and its selected peers as of October 4th, 2024, enabling an in-depth look into relative market positioning.

Table 1: General Company and Market Information (as of October 4th, 2024). This table represents large-cap companies within the Healthcare subsector Drug Manufactures - General. AstraZeneca was excluded from this analysis.

Table 2: Financial Performance Metrics (as of October 4th, 2024). This table represents large-cap companies within the Healthcare subsector Drug Manufactures - General. AstraZeneca was excluded from this analysis.

Table 3: Valuation Ratios (as of October 4th, 2024). This table represents large-cap companies within the Healthcare subsector Drug Manufactures - General. AstraZeneca was excluded from this analysis.
3. Valuation Multiples and Key Metrics
In our analysis of Amgen’s valuation, we compared its key multiples—EV/EBITDA, EV/Earnings, and P/E—against the sector benchmarks. This comparison provides insight into how the market perceives Amgen’s financial performance and growth potential relative to its peers.
Subsector Valuation Benchmarks
The subsector’s valuation multiples range widely, highlighting varied growth expectations and operational efficiencies among peers:
EV/EBITDA: Ranges from 7.3x to 45.4x, with an average of 14.8x.
EV/Earnings: Ranges from 13.6x to 124.6x, with an average of 49.1x.
P/E: Ranges from 12.6x to 107.0x, with an average of 42.4x.
These Healthcare subsector averages serve as valuable baselines for assessing Amgen’s market positioning and valuation premium.
Amgen’s Valuation Position
EV/EBITDA: Amgen’s multiple of 18.2x exceeds the subsector average of 14.8x, indicating a premium valuation. This suggests that the market values Amgen’s operational efficiency and cash flow generation highly, possibly due to its robust revenue streams and cost management.
EV/Earnings: At 52.7x, Amgen’s EV/Earnings multiple is also above the subsector average of 49.1x, reinforcing the view that investors place a high premium on the company’s ability to convert earnings into enterprise value. This may reflect strong expectations around Amgen’s long-term cash flows and profitability.
P/E Ratio: Amgen’s P/E ratio stands at 40.5x, slightly below the subsector average of 42.4x. This more modest valuation in terms of earnings suggests that investors view Amgen’s earnings growth as stable but not as aggressive as that of higher-growth subsector peers.
Interpretation and Insights
The positioning of these multiples offers insight into how the market values different aspects of Amgen’s performance:
Premium on Operational Strength: Amgen’s elevated EV/EBITDA and EV/Earnings ratios imply that investors recognize and value its operational efficiency and steady cash flows. This may be a reflection of Amgen’s established market presence, diversified revenue streams, and its ability to manage costs effectively, all of which drive sustained EBITDA and earnings.
Moderate Growth Perception: Amgen’s slightly lower P/E ratio, in contrast, indicates a tempered outlook on its growth relative to earnings. Investors appear to see Amgen as a stable performer rather than a high-growth stock, valuing its reliability over rapid expansion. This could stem from Amgen’s mature product portfolio or its growth strategies, which may be perceived as more conservative compared to peers.
Summary
In summary, Amgen’s valuation multiples highlight a market perception that balances the company’s strong operational foundation with moderate growth expectations. The premium in EV-based metrics suggests confidence in its cash flows and operational efficiency, while the P/E ratio signals a more cautious outlook on growth. Overall, Amgen is valued as a stable, efficient leader in its sector, with investor sentiment leaning toward reliability over aggressive growth potential.
4. Implied Valuation for Amgen Based on CCA
To assess Amgen's market valuation using the CCA approach, we applied subsector multiples to calculate the company's implied enterprise and equity values. This exercise highlights how Amgen’s valuation aligns with peer benchmarks and provides insights into investor expectations regarding its future performance.
Implied Valuation Analysis
As reflected in the table below, we used three key multiples—EV/EBITDA, EV/Earnings, and P/E—to derive a range of implied values.

Table 4: Implied Valuation based on CCA. Implied Enterprise Value, Net Debt, and Implied Equity Value are expressed in $B (billions). The Number of Share Out is expressed in M (millions).
This analysis shows that Amgen’s implied per-share valuation, based on sector multiples, ranges between $242.29 and $333.89. This range is notably higher than our DCF-derived intrinsic value of approximately $206.21. Interestingly, this range aligned with current market share price of $316.19 (as of October 4th, 2024)
Observations and Interpretation
EV/EBITDA Implied Value: The EV/EBITDA multiple, which captures operating performance, implies an enterprise value of $181.5 billion, translating to an equity value per share of $242.29. This suggests that Amgen’s operational efficiency and stable cash flows support a premium valuation relative to its DCF-derived intrinsic value.
EV/Earnings Implied Value: Using the EV/Earnings multiple, which reflects both net profitability and capital efficiency, yields a higher implied value of $291.05 per share. This price suggests that investors highly value Amgen's overall earnings quality and return on capital compared to its peers.
P/E Implied Value: The P/E multiple, which reflect market sentiment toward Amgen’s earnings growth, yields the highest implied value per share at $333.89. This figure might highlight market’s confidence in Amgen’s earnings potential, growth prospects, and capacity to sustain competitive returns.
Comparative Insights
The range of implied values from $242.29 to $333.89 indicates that, on a relative basis, the market values Amgen higher than its intrinsic DCF valuation of $206.21. Notably, this range aligns closely with Amgen’s current market share price of $316.19 (as of October 4, 2024), suggesting that the market may already be pricing in expectations for sustained growth, strategic positioning, and innovation beyond fundamental cash flows alone.
In summary, the subsector-based implied values reflect the market’s confidence in Amgen’s operational stability, profitability, and growth potential. However, this premium relative to the DCF-derived value may encourage investors to consider how broader market conditions and sector trends could impact Amgen’s long-term valuation sustainability.
5. DCF and Sensitivity Analysis
In our DCF model, we estimated a target price for Amgen of $206.21, assuming a WACC of 6.55% as of October 8, 2024. To explore how changes in capital costs and growth expectations might impact this valuation, we conducted a sensitivity analysis across various WACC and terminal growth rate scenarios.

Table 5: Sensitivity Analysis based on DCF analysis. The share price is expressed in $ (dollars).
Key Findings
Lower WACC Values (3.5% to 4%): These scenarios result in substantially higher implied share prices, ranging from $462.66 to $1,262.72. This indicates that under more favorable financing conditions, Amgen’s valuation would increase significantly, as lower capital costs enhance the present value of future cash flows.
Moderate WACC Values (5% to 6%): Implied share prices range between $213.32 and $447.20 in this bracket. This range represents a balanced view, where Amgen's valuation aligns more closely with the base DCF-derived target, reflecting average financing and growth conditions.
Higher WACC Values (6.5% and 7%): At these levels, implied share prices decrease, falling between $157.27 and $243.31. This highlights the valuation’s sensitivity to higher capital costs, which reduce the attractiveness of future cash flows, thereby leading to lower intrinsic values.
Conclusion
This sensitivity analysis demonstrates that Amgen’s intrinsic valuation is highly responsive to changes in WACC. A lower WACC significantly boosts implied value, suggesting Amgen’s stock becomes more attractive in low-interest or low-risk environments. Conversely, higher WACC scenarios show reduced valuations, indicating potential downside if capital costs rise. This analysis underscores the importance of stable financing conditions to support Amgen’s valuation.
6. Combined Analysis: Comparable Company Analysis and Sensitivity
The integration of Comparable Company Analysis (CCA) and Sensitivity Analysis offers a comprehensive perspective on Amgen's valuation profile, reflecting both market sentiment and intrinsic financial fundamentals:
Market-Based Premium: Amgen’s EV/EBITDA and EV/Earnings, which are elevated relative to subsector averages, indicate that the market is pricing in a premium. This premium likely reflects investor confidence in Amgen’s operational efficiency, resilience in cash flow generation, and its strategic positioning within the Drug Manufacturers - General subsector.
Intrinsic Value Discrepancy: The DCF sensitivity analysis underscores a key valuation gap: even under favorable assumptions for growth and cost of capital, Amgen’s DCF-derived intrinsic value of $206.21 per share remains below the range suggested by market multiples ($242.29 to $333.89). This divergence suggests that market sentiment—possibly driven by factors such as Amgen's robust portfolio, pipeline potential, and subsector stability—is likely contributing to the observed premium over intrinsic valuation.
7. Conclusion and Investment Implications
Amgen’s current share price of $321.79 (as of November 6, 2024) positions it within the premium range suggested by CCA, indicating that the market views the company favorably relative to peers. The premium observed in Amgen's EV/EBITDA multiple suggests strong investor confidence in Amgen’s efficiency and steady cash flow generation, while its more moderate P/E ratio aligns closer to subsector averages, reflecting a balanced view on its earnings growth potential.
Investment Implications
Amgen’s share price alignment with the CCA-derived values affirms the market’s positive sentiment toward the company. However, the discrepancy with the lower intrinsic value calculated from the DCF analysis suggests potential overvaluation if based solely on cash flow projections. This disparity prompts a careful consideration of Amgen’s premium, particularly in light of interest rate conditions, broader market sentiment, and healthcare subsector dynamics, which could significantly impact Amgen’s valuation.
In summary, while Amgen’s premium valuation signals investor optimism, it is essential for investors to weigh this against potential subsector volatility and evolving economic conditions. For those seeking stability in the healthcare sector, Amgen’s positioning remains strong, yet caution may be warranted for those relying strictly on cash flow fundamentals.
Disclaimer:
This research report contains information generated with the assistance of artificial intelligence. While every effort has been made to ensure accuracy and relevance, the analysis presented here may contain errors, omissions, or outdated data. Readers are encouraged to verify the information independently before making any decisions based on the content. This report is intended for informational purposes only and should not be considered professional or financial advice. Neither the author nor the AI service provider assumes responsibility for any inaccuracies or the use of the information provided.
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